Jul 29, 2024 · Sporadic pheochromocytoma is usually diagnosed on the basis of symptoms or an incidental discovery on computed imaging, whereas syndromic pheochromocytoma is frequently diagnosed earlier in the course of disease because of biochemical surveillance or genetic testing.

The classic triad includes headaches (likely related to elevated blood pressure, or hypertension), tachycardia/elevated heart rate, and diaphoresis (excessive sweating, particularly at night, also known as hyperhidrosis). [7] However, patients are unlikely to experience continuous symptoms.

Aug 28, 2024 · Pheochromocytomas are a type of paraganglioma. They are catecholamine-secreting tumors derived from chromaffin cells. They typically demonstrate a nesting (Zellballen) pattern on microscopy. This pattern is composed of well-defined clusters of tumor cells containing eosinophilic cytoplasm separated by a fibrovascular stroma.

With the increasing access to imaging more pheochromocytomas are diagnosed in the workup of adrenal incidentalomas. This may have changed the occurrence of the classic presentation with hypertension and the classic triad (headaches, sweating and palpitation). We reviewed 94 consecutive cases of pheochromocytomas.

Jun 30, 2022 · A pheochromocytoma is a rare tumor that forms in the middle of your adrenal gland. It's usually benign. Symptoms include high blood pressure and headaches.

Patients with pheochromocytoma are often described as presenting with the “classic triad” of diaphoresis, headache, and palpitations, typically accompanied by hypertension .

Mar 6, 2023 · Pheochromocytoma is a possibility in anyone with the classic triad of symptoms -- headache, sweating, and heart palpitations -- especially when there is high blood pressure (though high blood pressure is not always present).

Feb 12, 2013 · Pheochromocytomas can have variable clinical symptoms and signs that, when present, are often nonspecific. The most common symptoms are headache, palpitations, and sweating. Although the triad is 90% specific for the presence of a pheochromocytoma, the triad is uncommon, occurring in 10–36.5% of patients with pheochromocytoma [10, 18]. Other ...

Although the triad is 90% specific for the pres-ence of a pheochromocytoma, the triad is un-common, occurring in 10–36.5% of patients with pheochromocytoma [10, 18]. Other symp-toms and signs include pallor, nausea, flushing, weight loss, fatigue, psychologic symptoms such as anxiety and panic, sustained hyperten-

Mar 1, 2006 · Pheochromocytoma is typically associated with a symptom triad of headache, palpitations, and diaphoresis. Hypertension, either sustained or paroxysmal, is the clinical hallmark of pheochromocytoma and is commonly attributed to catecholamine excess.