Genetics is key to understanding what makes you unique — not just in appearance but also in personality and health.  A study of how genes are passed down from one generation to the next, genetics ...

Company expands multiomics portfolio with new roadmap technologies spanning genomics, spatial, single cell, CRISPR, and ...

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal ...

However, the mechanism of enhancer activation in advanced disease is unknown. Here, we used CRISPR-Cas9 screening to identify transcription factors that bind to the AR enhancer and modulate ...

In this research the team were able to identify genes that led to accelerated lymphoma growth in the pre-clinical model by using unique Cas12a-compatible mouse whole-genome CRISPR ‘libraries ... in ...

Dr. Puchalski: Yes, but with lots of other people. I enjoy partnering with people. I learn from others. So I probably would need to take a whole day to thank everybody that's been part of this. But ...

Single-cell CRISPR screening is a powerful method for biological ... Here, we report the results of an unbiased, whole genome CRISPR microscopy screen aimed at restoring nuclear envelope integrity ...

REACTR measures DNA synthesis by HIV RT using a CRISPR-Cas12a reporter system. We engineered a DNA template such that the complementary DNA (cDNA) synthesized by HIV RT activates the crRNA-Cas12a ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening. This method empowers scientists to systematically explore gene functions, ...