Given that alcohol is the most frequent functional group found in bioactive natural products and marketed drugs, and is a ...

Biosynthesis can be exploited for chemical synthesis in vitro or in cells like Escherichia coli by combining substrates with enzymes using recombinant methods. Medium- and branched-chain diols and ...

Overall, MMAI identified patients who potentially derived the greatest benefit with apalutamide in the SPARTAN trial. These data represent the first validation of MMAI in patients with nmCRPC, an ...

In a live event, Vinay Minocha, MD, discusses the addition of darolutamide to androgen deprivation therapy for in patients with metastatic hormone-sensitive prostate cancer. History of hypertension ...

"Although the α-D-ribofuranoside structure is frequently found in natural products, there have been fewer reports of the synthesis of α-D-ribofuranosides than of the β-anomers. Thus, the ...