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In a surprising discovery, scientists have found that the heart possesses 'sweet taste' receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can ...

Summary: New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds ...

Testing for anti-PF4 antibodies and parallel testing for ... administration of high-dose IVIG and in the presence of the Fcγ receptor II–blocking monoclonal antibody IV.3. Patient 2 has ...

ligand family (BAFF), and anifrolumab that binds the type I IFN receptor, both approved for treating SLE, as well as the anti-CD20 agent rituximab that is used off-label in refractory cases (9). The ...

The receptor kinase FERONIA (FER) controls ligand-induced complex formation of the immune receptor kinase FLAGELLIN SENSING 2 (FLS2) with its co-receptor BRASSINOSTEROID-INSENSITIVE 1-ASSOCIATED ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...

NOD-like receptors; PAMP, pathogen-associated molecular pattern; PF4, platelet factor 4; Pf EMP1, Plasmodium falciparum erythrocyte membrane protein 1; PRR, pattern recognition receptor; TLR, ...

Mitochondrial dysfunction underlies many prevalent diseases including heart disease arising from acute ischemia/reperfusion (I/R) injury. Here, we demonstrate that mitophagy, which selectively removes ...