Aclaris reports potential of ATI-2138 as a dual inhibitor for inflammatory diseases, with promising preclinical and clinical trial results. Aclaris Therapeutics, Inc. has announced the publication ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis.

Data Generated to Date Support Potential for Aclaris’ ATI-2138 to Impact Several Human Inflammatory Diseases - WAYNE, Pa., Feb. 12, 2025 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ ...

Data Generated to Date Support Potential for Aclaris' ATI-2138 to Impact Several Human Inflammatory Diseases - WAYNE, Pa., Feb. 12, 2025 (GLOBE NEWSWIRE) -- Aclaris Therapeutics, Inc. (NASDAQ: ACRS), ...

Most practicing sports medicine clinicians refer to the concept of “inflammation” many times a day when diagnosing and treating acute and overuse injuries. What is meant by this term? Is it a “good” ...

Through this mechanism, ATI-2138 has been shown in preclinical studies to effectively inhibit Th1, Th2 and Th17 cell activity, which are key T cells involved in a wide range of autoimmune, chronic ...

Chronic inflammation refers to a prolonged inflammatory response that involves a progressive change in the type of cells present at the site of inflammation. It is characterized by the ...

This development positions the molecule as a potential breakthrough in the treatment of autoimmune and inflammatory diseases. ATI-2138 exhibits the ability to selectively and potently block ...

Although research on cannabidiol (CBD) is still in its early stages, people are increasingly using it as an alternative treatment for various health conditions, including inflammation. Some ...

It has been known for many years that patients with a wide variety of nonhepatic infections can develop cholestasis (see [15,76] for excellent reviews). In 1901, in his classic textbook, The ...