Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and ...

Preclinical data previously published in the peer-reviewed journal, The Journal of Pain, 1 demonstrate robust antinociceptive effects of AV-101, similar to gabapentin, but with a better side effect ...

This study demonstrates that exposure to repeated and intermittent non-painful sound stress triggered chronic non-inflammatory hyperalgesia in mice, which provides experimental evidence for the causal ...

The cardinal features of classical neuropathic pain in the skin, such as seen in diabetes and in post-herpetic neuralgia, are allodynia (a painful response to stimuli not normally painful) to cold and ...

This was probably the outcome of a low threshold for visceral pain in the section of bowel in contact with the balloon. Colonic hyperalgesia of this kind, possibly a random occurrence, may be an ...

The somatic pain visual analogue score of subjects with fibromyalgia ... Although it is likely that endotoxin produces hyperalgesia, the common presence of bacterial overgrowth in fibromyalgia and IBS ...

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety, restlessness, brain fog, ...

The pain stems from inflammatory damage caused to nerves as the virus reactivates, leading to nerve pain known as hyperalgesia. The pain from anal herpes can be severe, especially during bowel ...

In the quest for a reliable way to detect any stirrings of a sentient “I” in artificial intelligence systems, researchers are turning to one area of experience—pain—that inarguably unites ...