Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies. Ashley started at The Scientist in 2018. Before joining the ...

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

CRISPR–Cas12a has a low tolerance for base ... Since we are developing in vivo medicines, our goal was to design editors that would eliminate even potential risks and edit only the target ...