A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

By activating a master epigenetic switch using CRISPR, naturally suppressed genes can be turned on, offering hope for Prader-Willi syndrome.

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and complex class of genetic ...

Centrosomes are nonmembrane organelles and responsible for microtubule nucleation and organization. Centrosomal RNAs have been identified in diverse model systems and are known to regulate gene ...

The CRISPR-Cas9 platform will be used to delete the ... effectively preventing immune cells killing them. The same mechanism has been identified as a potential survival pathway for cancer cells ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory ...

Understanding stress physiology and molecular response mechanisms in plants is essential for improving crop production and quality, particularly under ...

Originally discovered in bacteria as a defense mechanism against pathogens ... contributed significantly to the deciphering of the CRISPR-Cas9 mechanism in bacteria and my colleagues of the ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...