A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
In parallel, the emergence of clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (CRISPR-Cas9) revolutionized the field of genome engineering, allowing the ...
CRISPR-Cas systems are prokaryotic immune systems ... when delivered with adeno-associated viral gene therapy. SeqCas9, a Cas9 variant from the Streptococcus family, recognizes a simple NNG ...
After hours: February 7 at 7:59:52 PM EST ...
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