Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory ...

By activating a master epigenetic switch using CRISPR, naturally suppressed genes can be turned on, offering hope for Prader-Willi syndrome.

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and complex class of genetic ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

Scientists in the polo-obsessed nation have produced world's first genetically edited horses, designed to outrun champion ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...