CRISPR-Cas systems have been exploited for targeted genome editing. CRISPR-Cas13 mediated editing of RNA corrects a common mutation in the retinal degeneration gene USH2A, and restores usherin ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

When the cut is repaired, mutations are introduced that usually ... So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in ... strand break can result in insertion or deletion mutations, while repair pathways can be engineered to introduce ...

Genome editing with CRISPR-Cas is often associated with the induction of mutations. However, a team of researchers from the Swiss University of Lausanne now shows that it can also be used to ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...

Cas9, the first Cas protein repurposed for cutting DNA ... Scientific Institute found that while base and prime editing reduced undesired mutations relative to CRISPR-Cas9, they still generated some ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...