Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

While previous research has used CRISPR-based knockout screens to identify cancer-driving mutations, gaps remain in optimizing this technology for in vivo applications. To develop a more efficient ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

We only know two of the eight clubs that will go straight through to the round of 16, and 18 of the 24 teams who will be in the knockout rounds. That said, nine teams have already been eliminated ...

We only know two of the eight clubs that will go straight through to the round of 16, and 18 of the 24 teams who will be in the knockout rounds. That said, nine teams have already been eliminated with ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their own protein production, according to a study published in Cell Reports.

EditCo Bio, a leader in cutting-edge genetic engineering and cellular model solutions, today announced the launch of XDel Knockout Cells, an innovative product designed to revolutionize the field of ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.