A genetic breakthrough may soon bring bigger and better tomatoes and eggplants to the world. Scientists have mapped the ...
Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s disease, paving the way for potential new ...
In a study published in Nature Communications, researchers at the Beijing Institute of Stem Cells and Regeneration (BISCRM) ...
DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of ...
Mayo Clinic's Precision Mouse Engineering Core in Minnesota produces CRISPR/Cas9-mediated knockout and point mutant mice for researchers.
Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In 2020–2021, a “mysterious illness” struck ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
REACTR measures DNA synthesis by HIV RT using a CRISPR-Cas12a reporter system. We engineered a DNA template such that the complementary DNA (cDNA) synthesized by HIV RT activates the crRNA-Cas12a ...
To gain a better understanding of its anti-tumor mechanism, we perform a temporally resolved CRISPR-Cas9 screen to identify factors governing the DAC response. We show that DNA damage generated by ...
1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...
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