CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

In a landmark achievement for both Uganda and the global medical community, the United States Patent and Trademark Office ...

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today reported consolidated financial results for the fourth quarter and full year ended December 31, 2024, and provided ...

Genome-wide association studies (GWASs) have linked genetic variants to neuropsychiatric disorders, but their regulatory ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas ... highlighting its potential as an efficient and precise tool for gene editing applications. Establishment and robust expansion of human ...

Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...

Casgevy (exagamglogene autotemcel or exa-cel) became the first drug based on the CRISPR/Cas9 gene-editing technology ... The one-shot therapy is an ex vivo application of the technology, meaning ...

CRISPR-Cas systems are prokaryotic immune systems ... when delivered with adeno-associated viral gene therapy. SeqCas9, a Cas9 variant from the Streptococcus family, recognizes a simple NNG ...

His research explores the rise of generative AI and accelerated use of AI more broadly to advance drug and scientific discovery. Reuben leads Gartner's coverage of genomics, multiomics, cell and gene ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...