Single-cell CRISPR screening is a powerful method for biological ... Here, we report the results of an unbiased, whole genome CRISPR microscopy screen aimed at restoring nuclear envelope integrity ...

Researchers identify new height genes utilizing both CRISPR knockout gene screening and genome-wide association study data. An international collaboration of researchers combined two genetic methods ...

In their article published in Nature Methods, the researchers applied PERISCOPE to execute three whole-genome CRISPR screens to ... to analyze optical pooled screening data at scale." ...

This is by far the most common use of CRISPR. It’s called genome editing – or gene editing – but usually the results are not as precise as that term implies. CRISPR can also be used to make ...

The platform offers high-quality screening data and biological insight to address ... Horizon’s pooled format screens offer researchers access to highly robust whole-genome level analyses ...

A major new study in the UK has shown that combining whole-genome sequencing (WGS) and real-world clinical data at a national scale can help deliver tailored, personalised cancer therapy.

Among his recent work at Drexel is the development of technologies based on the CRISPR-Cas9 system for genome mapping and sequencing, which have broad applications in molecular diagnostics, cell/gene ...

Base and Prime Editing Offer Precision CRISPR-based systems that rely on traditional Cas nucleases like Cas9 cut through both strands of DNA which can lead to undesirable and even dangerous edits to ...