In this model, plectin deficiency suppresses tumor initiation and growth. We further demonstrate that CRISPR/Cas9-engineered human HCC cell lines with inactivated plectin display limited migration, ...
“The functional genomics field has gone through several waves of evolution, starting with circulating DNA expression screens, RNA interference (RNAi), transposon/retroviral insertion screening and the ...
Kennedy Jr. will divest his interests in several biopharma companies, including CRISPR Therapeutics and Dragonfly Therapeutics, if confirmed by the ...
Department of Chemical and Biomolecular Engineering (BK21 Four), Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea ...
Shares of CRISPR Therapeutics CRSP have lost more than 30% in the past year. Though the stock soared at the onset of 2024, thanks to the FDA approval of its one-shot gene therapy Casgevy for two ...
Sequences of siRNAs used in this study are provided in Suppl. Table 1. Generation of knockout cell lines and targeted CRISPR-Cas9 screen eIF2A knock-out HeLa and HEK293T-H-Kb cell lines were generated ...
CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...
CRISPR-Cas9 is one of the biggest discoveries of the 21st century. Since it was developed in 2012, this gene-editing tool has revolutionized biology research, making it easier to study disease and ...
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