Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen ...

Sickle cell disease is more than a genetic disorder, it is a daily fight for survival. The condition arises from a mutation in the hemoglobin gene, causing red blood cells to become rigid and ...

In 2019, the first CRISPR clinical trials were conducted to treat sickle cell diseases and in 2020, this treatment was ...

In children with sickle cell disease, hemoglobin and sickle cell hemoglobin (HbS) should be measured at presentation with arterial ischemic stroke (D). Urgent exchange transfusion should be ...

Clinical trials for exa-cel have shown promising results that it has been authorised by the FDA and MHRA for use in beta thalassemia and sickle cell disease. These successes make CRISPR technology, as ...

Mother and Child Department, Faculty of Medicine, University of Parakou, Parakou, Benin. In Benin, the prevalence of major sickle cell disease (HbSS) is estimated at 4.18% [4] and 25% of subjects ...

Background Sickle ... 4 Hb SC), and ten cases had sickled erythrocytes in the intervillous space (7 Hb SS and 3 Hb SC). Figure 2 shows representative images of the placental findings. Sample images of ...

Introduction The incidence of feto-maternal complications is high in women with sickle cell disease. The paucity of high-quality evidence has led to conditional recommendations for transfusional ...

and tragic deaths because of sickle cell disease across Africa. These children and families cannot wait any longer.” SCD is a genetic disorder characterized by the production of an abnormal form of ...