Background Until recently, determining penetrance required large observational cohort studies. Data from the Exome Aggregate Consortium (ExAC) allows a Bayesian approach to calculate penetrance, in ...

There are several traditional model systems commonly used to study cancer, including cell culture based, zebrafish and mouse models. These models all have their own unique advantages and limitations ...

48.2 x 32.4 cm. (19 x 12.8 in.) ...

Alzheimer’s disease (AD) is the most common neurodegenerative disorder with the majority of patients classified as sporadic AD (sAD), in which etiopathogenesis remains unresolved. Though sAD is argued ...