We and others have also reported that acute alcohol consumption produces analgesic effects, while chronic alcohol consumption results in hyperalgesia ... pathways, upstream regulators, and biological ...

Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and ...

Darapladib and antioxidants could effectively alleviate the stress-induced hyperalgesia by inhibiting ... The central mechanism of RISS pain should be further investigated, including the involved ...

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety ... response via Ca2+- ...

The use of correct terminology in the animal studies, avoiding the terms such as “pain” and “hyperalgesia”, and replacing by the hypersensitivity to noxious events, which has already discussed in ...

Hyperalgesia refers to increased pain sensation in response to a certain stimulus ... Price 30 has reviewed the ascending pathways, subcortical, and cortical centres involved in somatic sensation, and ...

According to published results, a novel opioid-free pathway may provide noninferior pain management compared with an opioid-containing pathway during the perioperative period in patients undergoing ...

A common genetic pathway may account for increased risk for atherosclerotic disease in patients with chronic widespread musculoskeletal pain.

Now, after 25 years of research, scientists at Vertex Pharmaceuticals figured out how to block this same pain pathway with suzetrigine, leading to a new pain medication for the FDA to approve.

Greater pain intensity in cancer survivors correlates with increased cigarette, e-cigarette, and cannabis use, but decreased alcohol consumption. Greater pain intensity in cancer survivors has been ...