Researchers at the Technion-Israel Institute of Technology have discovered a unique genetic mechanism that provides cells with rapid and efficient protection against viruses. The findings could lead ...

It therefore became of interest to study the uptake, metabolism and synthesis of adrenaline by mammalian brain. We have found that adrenaline is synthesized in the brain.

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism ... be exploited for chemical synthesis in vitro or in cells like Escherichia coli ...

If the MEP pathway in bacteria is blocked, for example by a drug, the bacteria can no longer produce a number of vital natural products and subsequently die. Human cells do not have the MEP ...

"We found that the manner in which tumor cells die after radiotherapy depends on the engagement of specific DNA repair pathways, particularly when radiation is given at very high, focused doses.

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications.

Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 301700, ...

In the same way that ChatGPT understands human language, a new AI model developed by computational biologists captures the language of cells to accurately predict their activities. In the same way ...

Hope is not passive wishing but an active, dynamic process. According to Hope Theory, hope involves two components: agency and pathways. Agency is the belief in one’s capability to act ...

The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team published its results in the journal Angewandte Chemie International Edition.

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...

Several major pathways for the utilization of carbohydrates are found in mammalian cells, and although present knowledge of these pathways is extensive, there is much to be learned regarding their ...