Prenatal exposure to neuroinflammation (cytokines) may provide a biomarker for the risk of later development of Alzheimer's ...

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

hyperalgesia, reduced social behaviors and cognitive deficits,” including memory deficits (Hein and O’Banion, 2009, page 2). Since memory loss is closely associated with both AD and ...

On 4 September, she defended her dissertation, titled "Nocebo Hyperalgesia and Pain Progression: Prediction, Acquisition, and Recovery." Both the healthy women and those with fibromyalgia were ...

The Central Nervous System and Pain Perception The central nervous system (CNS), comprising the brain and spinal cord, plays a crucial role in how the body perceives pain. Under normal circumstances, ...

Colonic hyperalgesia of this kind, possibly a random occurrence, may be an important contributory factor in the aetiology of the irritable colon syndrome.

Conclusions The development of oesophageal hyperalgesia is prevented by physiologically increasing parasympathetic tone. This effect is pharmacologically blocked with atropine, providing evidence that ...

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety, restlessness, brain fog, ...

First of all, it's because many of us have temperature sensitivities to either heat, cold or both. We have a larger physiological response to temperature than other people. We don't know a lot about ...

Furthermore, it was not possible to individually assess the characteristic symptoms and signs of neuropathic pain, such as allodynia, hyperalgesia, and burning pain, owing to inconsistencies in ...

The pharmacokinetics, safety, and tolerability of four topical lidocaine patches 5% continuously applied for 72 hours and changed every 12 or 24 hours were examined. In this randomized ...