TMEM16A (ANO1): A specific type of calcium-activated chloride channel that is involved in various physiological processes and has been implicated in several diseases. Cystic Fibrosis: A genetic ...

Vertex Pharmaceuticals (VRTX) stock has performed strongly since the turn of the year, gaining 14.6% and vastly outperforming the healthcare ...

Ivacaftor is a new CFTR potentiator that helps the CFTR channel ... CFQ-R = Cystic Fibrosis Questionnaire-Revised; FEV 1 = forced expiratory volume in 1 second. Mean change in sweat chloride ...

New Delhi: Pharmaceutical major Dr Reddy's has got approval from the Subject Expert Committee (SEC) functional under the ...

For example, cystic fibrosis is a condition in which a child inherits two mutated genes controlling a protein that regulates channels responsible for the movement of chloride across cells in the ...

and it is primarily caused by a deficiency or malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in the pancreatic duct epithelium (PDE) (62). The CFTR protein ...

in lung function improvement with an acceptable safety profile in patients with cystic fibrosis. Researchers conducted two randomized, double-blind phase 3 trials (SKYLINE VX20-121-102 and VX20 ...

Skin fibrosis is an often-painful condition wherein the skin thickens and hardens, making it difficult to move. And with no effective treatments currently available, patients are left with few avenues ...

NASCAR announced today it will launch a FAST (Free Ad-Supported Television) Channel called the NASCAR Channel. The NASCAR Channel goes live with exclusive launch partner Tubi on Wednesday ...

In people with CF, mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the CFTR protein to become dysfunctional. When the protein is not working correctly, it’s ...

New triplet therapy for cystic fibrosis Vertex Pharma already dominates ... in CF patients and was better at reducing levels of chloride in sweat, a biomarker for disease control.