Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

The core components of CRISPR-based genome-editing ... Harvard and Cyrus Biotechnology have now engineered two CRISPR nucleases, Cas9 and Cas12, to mask them from the immune system.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking ...

CREATE is a genome editing system that combines CRISPR/Cas9 with a modified LINE-1 retrotransposon machinery, enabling programmable and highly specific integration of large payload genes using only ...

CRISPR-Cas9 is one of the biggest discoveries of the 21st century ... Administering Casgevy involves a complex and time-intensive process. Patients undergo harvesting of their hematopoietic stem cells ...