CRISPR-Cas9 genome editing exploits the CRISPR-Cas system ... and low off-target cytosine base editor based on FrCas9 protein, demonstrating its effective application in various microorganisms.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

KAMPALA - Dr Matthias Magoola says the US Patent and Trademark Office (USPTO) has granted a patent for his invention of the first treatment of cancer using a novel composition of a guided Ribonucleic ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Not long after the development of CRISPR-Cas9 gene editing ... as the Genome Aggregation Database (gnomAD) that R37X, a naturally occurring mutation in the prion gene, reduced protein levels ...

Stanford researchers introduced affordable gene-editing kits ready for the classroom, aiming to make the field more accessible for high school students.

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.

By creating gene editors not found in nature, or optimizing existing editors, AI can improve the accuracy, effectiveness, and accessibility of gene editing.

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease.