Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

There are a significant number of words, phrases and acronyms that appear when talking about race and ethnicity which often change depending on the context of the conversation. Language is ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. High-throughput measurement of cellular traction forces at the nanoscale remains a ...

A pipeline for the analysis of CRISPR edited data. It allows the evaluation of the quality of gene editing experiments using targeted next generation sequencing (NGS) data (`targeted`) as well as the ...

These LNPs could encapsulate the Cas9 protein and guide RNA (gRNA) within LNPs. LNPs protected these components from enzymatic degradation and facilitated their uptake by cells. The specificity of the ...

This valuable study is a detailed investigation of how chromatin structure influences replication origin function in yeast ribosomal DNA, with a focus on the role of the histone deacetylase Sir2 and ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

Alveolar type 2 (AT2) cells maintain lung health by acting as stem cells and producing pulmonary surfactant. AT2 dysfunction underlies many lung diseases, including interstitial lung disease (ILD), in ...

“For example, the most well-known of these immunotherapies only benefits 20 to 30% of patients.” When they delivered the Cas13 package into tumor microenvironments in mice, they found that it silenced ...