Medscape1d
CAR T-Cell Therapy Safe in Those With Autoimmune Disease
CAR T-cell therapy for cancer leads to similar safety and cancer outcomes in patients with and without preexisting autoimmune ...
Cure Today11h
Phase 2 Trial of Firi-Cel CAR T-Cell Therapy Discontinued in Lymphoma
The FIRCE-1 trial investigating the CAR T-cell therapy firi-cel in relapsed/refractory large B-cell lymphoma has been ...
Medscape2d
Promise for CAR T-Cell Therapies in Solid Tumors?
CAR T-cell therapies have demonstrated efficacy in treating blood cancers but, so far, their safety and effectiveness in ...
No evidence that CAR T cell therapy causes secondary cancers, large study shows
Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the ...
GEN10d
Making Strides Toward Off-the-Shelf CAR T Cell Therapy for Cancer
A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.
Science Daily1d
Gene modification could improve cancer treatment's success rate
A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...
STAT12d
CAR-T cells can arm other immune cells with engineered proteins to fight cancer, study says
Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...
CAR-T cells can arm bystander T cells with CAR molecules via trogocytosis
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
Hosted on MSN13d
Viral protein Nef enables a step toward off-the-shelf CAR T cell therapy for cancer
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a ...
New gene modification enhances CAR-T cell effectiveness against cancer
Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for ...
Upstate cancer survivor celebrates recovery with innovative CAR T-cell treatment
On this World Cancer Day, Chris Vogelsang, a cancer survivor from upstate New York, is celebrating his recovery thanks to a ...
technologynetworks9d
Study Finds No Evidence CAR T-Cell Therapy Causes Secondary Cancers
A study of 783 patients treated with CAR T cell therapy found no evidence that the therapy itself caused secondary cancers.