CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

The CRISPR/Cas9 gene-editing system, based on a bacterial immune response against viruses, has been applied to human genome editing and was recently implemented in the first Food and Drug ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and complex class of genetic ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...