CRISPR-Cas systems have been exploited for targeted genome editing. CRISPR-Cas13 mediated editing of RNA corrects a common mutation in the retinal degeneration gene USH2A, and restores usherin ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in ... strand break can result in insertion or deletion mutations, while repair pathways can be engineered to introduce ...

This dissertation focuses on the glial protein GFAP and Alexander disease, a severe neurological disorder primarily affecting young children. Mutations in the GFAP gene disrupt astrocyte function, ...

The gene-edited GMOs to be exempted are those classed as the products of SDN1 (gene disruption) and SDN2 (gene modification). As with the recent deregulation of gene-edited GMOs in England, the New ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

A groundbreaking study led by USC Assistant Professor of Computer Science Ruishan Liu has uncovered how specific genetic mutations influence cancer treatment outcomes-insights that could help doctors ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...