“Almost half of all bacteria and the large majority of archaea on planet Earth have an endogenous CRISPR-Cas system in them,” he said. “One of the great things to do is just to repurpose the ...

AIST researchers, in collaboration with JAMSTEC, Hokkaido University and Tohoku University, have succeeded in cultivating an ...

AIST researchers, in collaboration with JAMSTEC, Hokkaido University and Tohoku University, have succeeded in cultivating an ...

CRISPR/Cas systems are widespread RNA-mediated prokaryotic ... suggesting that phages have evolved counter strategies to thrive within bacteria despite these mechanisms 2. Thus, both bacterial ...

Accompanying CRISPR sequences, there are 4-10 CRISPR-associated genes (cas), which are highly conserved and encode the Cas proteins. Cas proteins conduct adaptive immunity in prokaryotes (bacteria ...

Bacteria and archaea possess adaptive immunity against foreign genetic elements using CRISPR–Cas systems. Upon infection, new foreign DNA sequences are captured and integrated into the host CRISPR ...

The microbes that make up an organism’s microbiome have a range of effects on its health. Scientists use CRISPR systems to genetically manipulate specific bacterial species, for instance those found ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

It happened probably in 2007 when a paper appeared in Science, describing for the first time the possible function of the CRISPR-Cas system as an antiviral defense system in bacteria. And we ...

So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own genome to guide the Cas proteins, and the odd patterns of these bits of ...

But how exactly do these ancestors work? The acronym CRISPR is used to refer to the repeated sequences of DNA found in bacteria and archaea. A simulated strand of DNA. Image source: billionphotos ...