CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

"Our research interest is to identify these genes in order to better treat diseases." CRISPR screening methods can be used to systematically examine genes for their function in cells. "CRISPR is ...

A new study reveals that modifying the CUL5 gene enhances CAR-T cell therapy for leukemia and lymphoma. This improves cell ...

Visualizing cells after editing specific genes can help scientists learn new details about the function of those genes. But using microscopy to do this at scale can be challenging, particularly when ...

A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...

CRISPR-based technologies can be quite powerful in the journey ... highlighting the approach’s potential to screen for bacteria amenable to genome editing without the need to cultivate and test ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...