A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Scientists from the Cancer Dependency Map (DepMap) at the Broad Institute of MIT and Harvard and Columbia University have ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

EditCo Bio, a leader in cutting-edge genetic engineering and cellular model solutions, today announced the launch of XDel Knockout Cells, an innovative product designed to revolutionize the field of ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

Intellia is also developing its wholly-owned NTLA-2002, an investigational in vivo CRISPR-based therapy designed to knock out the KLKB1 gene in the liver and enable lifelong control of hereditary ...