Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

While previous research has used CRISPR-based knockout screens to identify cancer-driving mutations, gaps remain in optimizing this technology for in vivo applications. To develop a more efficient ...