It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

CRISPR-Created Animal Models: The Technical Lowdown from thescientistllc on Vimeo. Creating reproducible animal models for long-term studies can often be problematic due to the complexity of the ...

Hybrid animals, or chimeras ... Through techniques like CRISPR-Cas9, scientists can edit the genome with precision, inserting specific genes from one species into another. The resulting organisms ...

Working with animal models, researchers in laboratories around the world have already used CRISPR to correct major genetic flaws, including the mutations responsible for muscular dystrophy ...

By using CRISPR, we are not affecting the chromosomes, so the animal is more fit, which results in longer viability in the wild and a higher rate of population suppression. Our laboratory is very ...

However, CRISPR has also been adapted to do other things too, such as turning genes on or off without altering their sequence. There were ways to edit the genomes of some plants and animals before ...

The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK ...

In response to this challenge, Caribou has developed CRISPR hybrid RNA-DNA guides (chRDNAs; pronounced “chardonnays”) that direct substantially more precise genome editing compared to all-RNA ...