eLife8d
Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling
We use CRISPR-engineered RPE-1 cells to demonstrate that the U-box ... IFT172 and HsIFT172 used in this study. (B) Cartoon representation of the AlphaFold predicted structural model for a complex ...
STAT1d
The CRISPR companies are not OK
Gene editing promised a revolution, but biotech layoffs, stock slumps, and industry struggles reveal a stark reality: CRISPR ...
CRISPR technique helps reveal how bean genes could improve nitrogen fixation
Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...
Quanta Magazine2d
The Poetry Fan Who Taught an LLM to Read and Write DNA
By treating DNA as a language, Brian Hie’s “ChatGPT for genomes” could pick up patterns that humans can’t see, accelerating ...
MIT Technology Review11d
Mice with two dads have been created using CRISPR
It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.
News Medical8d
Breakthrough in gene-editing with Cas12a for modeling human diseases
Cas enzymes are required to cut specific sections of DNA or RNA during CRISPR experiments. CRISPR is a revolutionary gene-editing tool widely used for cancer research, which is currently in the ...
News Medical8d
Researchers create random versions of human genomes to study disease
Researchers from the Wellcome Sanger Institute, Imperial College London, Harvard University in the US and their collaborators used CRISPR prime ... building blocks of DNA and RNA.
The Hindu27d
Putting the gene editing tool to use
and Cas9 (which stands for CRISPR- associated Protein 9) cuts DNA strands at a specific location, creating a gap that can be filled with new DNA. Doudna and Charpentier shared the Nobel Prize in 2012.