A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

By creating gene editors not found in nature, or optimizing existing editors, AI can improve the accuracy, effectiveness, and accessibility of gene editing.

Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in ...

Analysis of CRISPR/Cas9 edited cells is done to check the efficacy of the system in introducing mutations (insertions, deletions, or substitutions) in the DNA sequences of the edited cell population.

The discovery of the CRISPR/Cas9 gene editing tool won two researchers, Emmanuelle Charpentier and Jennifer A. Doudna, the ...

Editas and CRISPR are probably most closely linked as they both pursued Sickle Cell Disease (SCD ... Even with the only approved CAS9 based treatment out there, CRISPR is still years away from ...

By using genetic material from two male mice, researchers successfully created pups that survived to adulthood, offering ...