DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of ...

(A) A diagram outlines the drug treatment experiment ... (C through K) Representative light sheet microscopy scanning pictures of brains from ccm2 CRISPR adult zebrafish on Tg(fli1:EGFP) background.

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal ...

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CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

REACTR measures DNA synthesis by HIV RT using a CRISPR-Cas12a reporter system. We engineered a DNA template such that the complementary DNA (cDNA) synthesized by HIV RT activates the crRNA-Cas12a ...

1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...

5,15 Both technologies are based on the CRISPR-Cas system but utilize different CRISPR-associated proteins, Cas13 for SHERLOCK and Cas12a for DETECTR, to achieve their highly specific diagnostic ...

Using CRISPR ... system. CINDELA utilizes a previously unexplored idea of introducing CRISPR-mediated DNA double-strand breaks (DSBs) in a cancer-specific fashion to facilitate specific cell death. In ...