Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating ...
Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out ...
The core components of CRISPR ... structure-based computational tools to design proteins that evade the immune response. After Zhang's team identified immunogenic sequences in Cas9 and Cas12 ...
New study reveals that TLE6 protein deficiency causes male infertility in mice. These findings suggest potential genetic ...
Associate Professor Qing Zhong shared insights on AI breakthroughs in proteomics and multiomics, challenges in data sharing ...
Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking ...
July 22, 2024 — The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for ...
Here, we introduce CRISPR-Enabled Autonomous Transposable Element (CREATE), a genome editing system that combines the programmability and precision of CRISPR/Cas9 with the RNA-mediated ... multiple ...
Despite its potential, the CRISPR/Cas9 system for genome editing is accompanied by a series of limitations and challenges. These issues include off-target effects, complex genome structures ... to ...