This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out ...

"This type of gene editing should also allow for the treatment of diseases whose origin is not genetic or whose origin cannot ...

A patient would only need a single treatment. CRISPR-Cas9 is comprised of two parts. A guide RNA will target the specific sequence within the genome, and Cas9 will be used as the molecular ...

Gene editing involves changing the sequence of DNA using specific ... Interspaced Short Palindromic Repeats, and Cas9 (which stands for CRISPR- associated Protein 9) cuts DNA strands at a specific ...

CRISPR-Cas9 pioneer presented with National Medal ... It uses a guide RNA to target the desired DNA sequence and the Cas9 enzyme as molecular scissors. Zhang is widely regarded as a fellow pioneer ...

A first patient has been treated in a trial of an Allergan and Editas drug based on CRISPR/Cas9, a technology that ... but using CRISPR its sequence can be edited to restore its normal function ...

By combining the precision and programmability of CRISPR/Cas9 with the retrotransposition process of L1, we inserted a 1.1 kb sequence comprising a promoter and green fluorescent protein (GFP) into ...

These patterns are the basis of a primitive immune system that bacteria use to ‘remember’ the DNA of viral invaders by incorporating the DNA sequence of the virus within the CRISPR patterns. The Cas9 ...