Advances in CRISPR technologies promise to accelerate the burgeoning pipeline of gene-editing therapies and broaden access to these disease-altering therapies.

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

“CLIC has already established an academic manufacturing network for a CD19 CAR-T, with centralised plasmid and vector production ... from gene-editing technologies such as TALEN and CRISPR/Cas9 ...

DNA-In® CRISPR Transfection Reagent MTI-GlobalStem’s new DNA-In® CRISPR transfection reagent delivers Cas9 in vitro with high efficiency and low toxicity to support targeted genome editing ...

Experts hailed exciting news for some people with sickle cell disease in England as the health watchdog decided to grant ...

Abcam’s new CRISPR-Cas9 knockout (KO) cell lines provide reproducible, single gene KOs that support the interrogation of the relationship between genotype and phenotype.

It's clear though that these companies need time. Even with the only approved CAS9 based treatment out there, CRISPR is still years away from achieving its potential. In a recent update to ...

We recently published a list of 9 Stocks Jim Cramer Talked About. In this article, we are going to take a look at where CRISPR Therapeutics AG (NASDAQ:CRSP) stands against other stocks that Jim Cramer ...

Get Instant Summarized Text (Gist) CRISPR nucleases, Cas9 and Cas12, have been engineered to evade immune detection, addressing a key challenge in CRISPR-based therapies. By identifying and ...

Bring up germline editing, and most scientists cringe. The idea behind the notorious CRISPR-baby scandal, editing reproductive cells or embryos tinkers with DNA far beyond just the patient—any changes ...