CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

New gene therapy modalities, such as CRISPR guide RNA (single guide ribonucleic acid [sgRNA]) and messenger RNA (mRNA), ...

This manuscript describes a fundamental investigation of the functioning of Cas9 ... PAM recognition and underscores the importance of fine-tuning the flexibility of the PAM-interacting cleft as a key ...

Attorney General Pam Bondi vowed to end the "weaponization" of government, the "two-tiered" system of justice and crack down on states and officials who attempt to interfere with the enforcement ...

Traditionally, CRISPR-Cas9 has been the predominant system for gene editing, but limitations such as sequence constraints and off-target effects have driven the search for alternative tools.

“It’s the end of the weaponization of government and getting back to prosecuting violent crime and giving our great men and women the tools that they need in law enforcement,” Bondi told Fox ...

When Eric Holder became attorney general, the scene was the same. But when Pam Bondi was sworn in as the newest attorney general, she took the oath in the Oval Office — with Donald Trump nearby ...

WASHINGTON – Moving swiftly to align the Justice Department with President Donald Trump’s agenda, Attorney General Pam Bondi on Wednesday issued a flurry of directives including the creation ...

Attorney General Pam Bondi warned sanctuary cities they 'are going to be next' if local officials continue to harbor and protect illegal aliens over the safety of citizens. Speaking with Fox ...

Pam Bondi is the first attorney in history to have been a lobbyist for foreign governments. She also just disbanded the FBI’s Foreign Influence Task Force. By Steve Benen There were quite a few ...