Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

Most recently, CRISPR-Cas9 based ‘knock-out’ of two genes in tomato plants increased their sweetness with no loss in weight. Similar studies on other plants and fruits will surely follow.

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

Thermo Fisher Scientific, Horizon Discovery, OriGene Technologies, QIAGEN, and GeneCopoeia Lead the Competition MicroRNA ...

Cas12a, supports a larger range of genetic edits, including incorporation or deletion of genetic material, i.e. knock-in and knock out (see image ... using Crispr/Cas9 encapsulated in their ...

Stable SlNTRC knockout mutants were then generated in tomatoes using CRISPR–Cas9-mediated gene editing. The homozygous mutant line experienced substantial delays in vegetative growth and an ...

July 22, 2024 — The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for ...

Intellia is also developing its wholly-owned NTLA-2002, an investigational in vivo CRISPR-based therapy designed to knock out the KLKB1 gene ... CRSP CRISPR/Cas9 genome-edited cell therapy ...

It allows the evaluation of the quality of gene editing experiments using targeted next generation sequencing (NGS) data (`targeted`) as well as the discovery of important genes from knock-out or ...