This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

Beans are a key food at the dietary level, boasting high nutritional value and constituting the most directly consumed legume ...

The platform enables direct, unbiased genome-wide identification and quantification of the exact position of double strand DNA breaks in edited cells.

Both Cas9 and Cas12a cleave DNA, but they differ in how they cut the molecule.