CRISPR Breakthrough Unlocks the Genetic Blueprint for Super-Sized Produce
A genetic breakthrough may soon bring bigger and better tomatoes and eggplants to the world. Scientists have mapped the ...
Scientists Identify Key Protein Driving Alzheimer’s Brain Cell Death
Scientists have identified the 1N4R tau isoform as a key driver of Alzheimer’s disease, paving the way for potential new ...
Genome-edited stem cells reveal new hope for obesity treatment without muscle loss
In a study published in Nature Communications, researchers at the Beijing Institute of Stem Cells and Regeneration (BISCRM) ...
Bacterial 'jumping genes' can target and control chromosome ends
DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of ...
eLife14d
Genetic Inactivation of the β1 adrenergic receptor prevents Cerebral Cavernous Malformations in zebrafish
(A) A diagram outlines the drug treatment experiment ... (C through K) Representative light sheet microscopy scanning pictures of brains from ccm2 CRISPR adult zebrafish on Tg(fli1:EGFP) background.
C&EN15d
PAM-Independent CRISPR-Cas12a System for Specific Assays of Single Nucleotide Variants
Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Ministry of Education), Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering, Hunan Normal ...
Nature26d
CRISPR-Cas9 genome editing articles from across Nature Portfolio
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
C&EN27d
Rapid Enzymatic Assay for Antiretroviral Drug Monitoring Using CRISPR-Cas12a-Enabled Readout
REACTR measures DNA synthesis by HIV RT using a CRISPR-Cas12a reporter system. We engineered a DNA template such that the complementary DNA (cDNA) synthesized by HIV RT activates the crRNA-Cas12a ...
The Lancet1mon
CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination
1Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-5900 USA 2Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical ...