A major concern in the applications ... CRISPR/Cas9 derivatives with enhanced precision. In this review, we summarize these technological advancements and discuss about the current challenges in the ...

In this mini-review article we discuss the application of gene therapy ... the CRISPR/Cas9 technology, and the award of the Nobel Prize in Chemistry to the inventors has opened up an exciting new ...

Another application ... cell disease (BEAM-101 treatment) and is expected by the company to be less risky than “simple” CRISPR-Cas9 therapies. It might also be more efficient, resulting in a higher ...

CRISPR-Cas9 is one of ... The most obvious application is treating genetic diseases such as sickle cell disease, caused by a mutation in the HBB gene. That is exactly the focus of Casgevy, the ...

CRISPR Therapeutics uses the CRIPSR-Cas9 technology ... in blood diseases, cancer therapy, and diabetes. What makes CRISPR attractive is how advanced its research program is for its blood therapy ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Some with severe sickle cell disease in England will now be able to access landmark CRISPR gene editing therapy ... The discovery of the CRISPR/Cas9 gene editing tool won two researchers ...

Bristol Myers Squibb's FDA nod for Breyanzi (liso-cel) in relapsed/refractory CLL/SLL boosts its CAR T-cell portfolio, ...