CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and complex class of genetic ...

Scientists at UC San Francisco have pioneered a groundbreaking approach to fighting cancer using engineered fat cells. By ...

Researchers at the University of California, San Francisco have uncovered a mechanism that could transform the fight against ...

Running these different assays in parallel is “hugely attractive”, Kampmann says. The CRISPR-activation screens in particular “are really very powerful as a supplement to loss-of-function ...

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

By exploring single cell RNA-sequencing data from clinical trials using CRISPR-Cas9 engineered T cells, the researchers found that a clinical trial using a different protocol, where scientists edited ...

Could advances in CRISPR technology be the solution ... used second-generation CAR T cells to achieve sustained T cell activation and remission for the majority of patients tested.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

CRISPR-Cas9 technology holds promise for treating inherited ... The LTR serves as HIV’s promoter to activate transcription, 2 so Lai wondered if the viral plasmids could enable a cell to produce viral ...