January 31, 2025 expert reaction to NICE final draft guidance on exagamglogene autotemcel (exa-cel) for severe sickle cell disease . Scientists comment on final draft guidance fro ...

Known as Zynteglo in Europe where it is approved to treat the rare blood disorder beta-thalassemia ... triggering a mutation or disrupting a mechanism that guards against a cell becoming cancerous.

The results of a study in mice by Van Andel Institute (VAI) scientists suggest that a person’s lifetime risk for cancer may begin before they are even born. Headed by J. Andrew Pospisilik, PhD ...

Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and leading to fractures. Although the condition is well recognized, Dominique ...

Genetic mechanisms of resistance to kinase inhibitors include mutations in the target receptor and mutations or gene amplification of compensatory receptors or other signaling effectors.

Immune evasion is a strategy used by pathogenic organisms and tumours to evade a host's immune response to maximize their probability of being transmitted to a fresh host or to continue growing ...

Request permissions for this article. Division of Hematology and Oncology, Department of Medicine (P.B.F.), Vanderbilt University Medical Center, Nashville, TN. Vanderbilt Institute for Infection, ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.