Despite advances in anticoagulant therapies, bleeding remains a critical concern.Traditionally, the definition of major ...

With no differences between single or dual antiplatelet therapy or anticoagulants at 6 months, an RCT is warranted for clarity.

A LANDMARK Australian-New Zealand study of 586 patients with spontaneous coronary artery dissection (SCAD), has identified ...

Data taken from [59–62]. Warfarin is the most well-understood oral anticoagulant in terms of genetics. CYP2C9 and VKORC1 polymorphisms lead to variable dose response and complicate warfarin therapy.

A placebo-controlled phase 3 trial of asundexian in older patients who aren’t eligible for directly-acting oral anticoagulants ... in patients in need of antithrombotic treatment,” said ...

Introduction The purpose of this study is to evaluate the safety and efficacy of two different antithrombotic strategies, dual antiplatelet therapy (DAPT, aspirin and ticagrelor) and direct oral ...

Learn the pathophysiology of atherothrombosis and mechanisms by which aspirin, P2Y 12 inhibitors and anticoagulants exert antithrombotic effect. Describe key randomised clinical trials of ...

Phase III PRESTIGE-AF trial shows that direct oral anticoagulants significantly lower the risk ... “The PRESTIGE-AF trial is the first completed phase 3 trial of antithrombotic stroke prevention in ...

For patients requiring long-term anticoagulation, monotherapy with direct oral anticoagulants or vitamin K antagonists is recommended to minimize bleeding. Ongoing trials aim to clarify optimal ...