An often-overlooked mechanism of gene regulation may be involved in the failure of antifungal drugs in the clinic ... used the known mode of action of fluorocytosine on A. fumigatus as the ...

Human fungal pathogens exemplify a severe threat to health due to their complex infection strategies and the host's immune system's failure to eradicate ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

The University of Exeter has launched a new round of funding to tackle the growing global challenge of fungal antimicrobial resistance (fAMR). The FAILSAFE project (Fungal AMR Innovations for ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell ...

A groundbreaking cannabinoid-based antimicrobial, Silvanex, fights drug-resistant infections with a synergy of silver, CBC ...

“The exact mechanism of action of D13 is not fully understood yet but ... some first and second generation compounds also demonstrated excellent antifungal activity at very low drug concentrations, ...

There were more frequent gastrointestinal side effects with ceftobiprole but that was expected given the drug's mechanism of action. Ceftobiprole has qualified infectious disease product (QIDP ...