Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) are major complications that occur in severely ill patients who require intensive care treatment. CIP and CIM affect the ...

After stopping long-term treatment with Acthar Gel, patients may experience hypothalamic-pituitary-adrenal axis suppression, which results in reduced cortisol production. As cortisol is necessary ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

Water and sodium retention during severe hypothyroidism create a state of volume depletion, low extracellular fluid osmolality and increased water retention. The hypothyroid population is ...

Once activated, PSC also secrete endogenous factors that can further activate transformed PSC via autocrine pathways. Signalling pathways ... retarding the development of exocrine and endocrine ...