The pathophysiology of residual sleepiness in treated obstructive sleep apnoea (OSA) remains poorly understood. Animal models ...

Background Whether inhaled corticosteroids (ICSs) reduce major adverse cardiovascular events (MACEs) in people with chronic obstructive pulmonary disease (COPD) is debated. Objectives To establish, ...

Background Sampling of peripheral pulmonary lesions (PPLs) abutting the pleura carries a higher risk of pneumothorax and complications. Although typically performed with image-guided transthoracic ...

1 Department of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan 2 Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, ...

Air Travel Working Party: Dr R K Coker (chair), Dr D A R Boldy, Dr R Buchdahl, Mr D Cramer, Professor D Denison, Wing Commander D P Gradwell, Professor J M B Hughes, Dr J A Innes, Dr A O C Johnson, Dr ...

Lymphoid interstitial pneumonitis (LIP) is a rare clinicopathological entity that may be associated with common variable immune deficiency (CVID) and may lead to respiratory failure and death. Some ...

1 Department of General Practice, Division of Public Health, Academic Medical Center, University of Amsterdam, The Netherlands 2 Department of Clinical Epidemiology, Leiden University Medical Centre, ...

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...

BACKGROUND Pulmonary rehabilitation programmes improve the health of patients disabled by lung disease but their cost effectiveness is unproved. We undertook a cost/utility analysis in conjunction ...

Background The natural history and time course of the onset of exacerbation events of chronic obstructive pulmonary disease (COPD) is incompletely understood. Methods A prospective cohort of 212 ...

The North West Lung Centre, University Hospital of South Manchester NHS Foundation Trust, Wythenshawe Hospital, Manchester, UK Dr A Bentley The North West Lung Centre, University Hospital of South ...

Background Longitudinal studies investigating impact of exogenous sex steroids on clinical outcomes of asthma in women are lacking. We investigated the association between use of hormonal ...